100-Mile Western States Endurance Run: A physiologic stress laboratory

Hyponatremia in the 2009 161-km Western States Endurance Run.

PURPOSE To determine the incidence of exercise-associated hyponatremia (EAH), the associated biochemical measurements and risk factors for EAH, and whether there is an association between postrace blood sodium concentration ([Na+]) and changes in body mass among participants in the 2009 Western States Endurance Run, a 161-km mountain trail run. METHODS Change in body mass, postrace [Na+], and...

Quercetin ingestion does not alter cytokine changes in athletes competing in the Western States Endurance Run.

The purpose of this study was to measure the influence of quercetin on plasma cytokines, leukocyte cytokine mRNA, and related variables in ultramarathoners competing in the 160-km Western States Endurance Run (WSER). Sixty-three runners were randomized to quercetin and placebo groups and under double-blinded methods ingested 1000 mg/day quercetin for 3 weeks before the WSER. Thirty-nine of the ...

Physiologic Measures of Animal Stress during Transitional States of Consciousness

Determination of the humaneness of methods used to produce unconsciousness in animals, whether for anesthesia, euthanasia, humane slaughter, or depopulation, relies on our ability to assess stress, pain, and consciousness within the contexts of method and application. Determining the subjective experience of animals during transitional states of consciousness, however, can be quite difficult; f...

A new physiologic race

Physical working capacity and mile run performance in adolescent boys.

The degree of generality between the endurance characteristics of the one mile run and PWC170 tests was examined with a group of fifteen year old boys who performed both tests once a week for three weeks. A significant improvement in performance of both tests was found between trials 1 and 2, which was sustained between trials 2 and 3. These results suggest that norm scales regarding performanc...